Tobias MÜLLER | Cited by 5,016 | of University of Leipzig, Leipzig | Read 150 publications | Contact Tobias MÜLLER At the centre of the experience, however, is the performance itself, which may be enhanced on an aural, visual or even tactile level. CYP2R1 About. Cyclophilin A (CypA) is required for viral replication, and CypA inhibitors are in development. (DOC), Association of IL28B rs8099917 genotypes with viral clearance with and without therapy. At Oregon State Treasury, we prioritize long-term thinking, prudent financial management, and resources to help Oregonians invest in themselves and their families. Browse the most recent Oregon obituaries and condolences. of Infectious Diseases, Department of Internal Medicine II, Division of Hepatology, Real-World Clinical Management of Patients with Primary Biliary Cholangitis—A Retrospective Multicenter Study from Germany, Gadoxetic acid-enhanced MRI in primary sclerosing cholangitis: added value in assessing liver function and monitoring disease progression, Veränderungen der Hepatitis-C-Virus-Genotyp-1a/1b-Verteilung zwischen 2004 und 2018 in Deutschland – eine Analyse von 17093 Patienten aus verschiedenen Real-World-Registern, HBP-enhancing hepatocellular adenomas and how to discriminate them from FNH in Gd-EOB MRI, Genetic variants of interleukin 1 beta are associated with viral hepatitis-related HCC in Caucasian patients, Ecto-Nucleotide Triphosphate Diphosphohydrolase-2 (NTPDase2) Deletion Increases Acetaminophen-Induced Hepatotoxicity, Clinical and molecular characterization of the human kidney as extrahepatic site of hepatitis E virus infection, Gender disparity in the association of interleukin-10 and interleukin-12 polymorphisms with the progression of hepatitis B virus infection in Caucasians, Evolution of hepatitis C virus genotype 1a vs 1b distribution reflects profound changes in HCV epidemiology in Germany - analysis of 17,093 patients from five consecutive registries including the German hepatitis C-registry (DHC-R), Geschlechtsabhängige Assoziation von genetischen Varianten von Interleukin 10 und 12 mit dem Verlauf der Hepatitis-B-Virus-Infektion bei kaukasischen Patienten, Evolution of hepatitis C virus genotype 1a vs. 1b distribution reflects profound changes of HCV epidemiology in Germany between 2004 and 2018 - Analysis of 17,093 patients from five consecutive registries including the German Hepatitis C-Registry (DHC-R), Assoziation von rs16944 im Interleukin-1-beta-Gen mit der Entwicklung eines hepatozellulären Karzinoms in kaukasischen Patienten mit chronischer Virushepatitis, Ten‐year follow‐up of a randomized controlled clinical trial in chronic hepatitis delta, Treatment outcomes in hepatitis C virus genotype 1a infected patients with and without baseline NS5A resistance‐associated substitutions, Sofosbuvir monotherapy fails to achieve HEV RNA elimination in patients with chronic hepatitis E – The HepNet SofE pilot study, Resistance‐associated substitutions in patients with chronic hepatitis C virus genotype 4 infection. Meine Texte sind im Süddeutschen Magazin, der Weltwoche und dem Guardian erschienen, ich schreibe regelmässig für die österreichische Tageszeitung Der Standard und das Magazin Falstaff. To achieve a better distribution of lidocaine in the tracheobronchial tree, spray catheters have been developed, allowing nebulization of the local anesthetic solution. Functional host genetic single nucleotide polymorphisms (SNPs) in the APOE gene encoding apolipoprotein E (apoE) - a major structural LDL compone... Background: This polar guanosine analog improves the sustained virological response (SVR) rates, but may induce hemolytic anemia. This stress induces a cyto-protective signaling cascades termed the unfolded protein response (UPR) aimed at restoring homeostasis. Epub 2012 Nov 28. (DOC), Linkage disequilibrium of SNPs in Rukaiyah Adams John Russell Rex Kim Rick Miller, Jr. Tobias Read Steve Rodeman Vice Chair Member Member Member State Treasurer PERS Director OREGON INVESTMENT COUNCIL Agenda February 1, 2017 9:00 AM Oregon State Treasury Investment Division 16290 SW Upper Boones Ferry Road Tigard, OR 97224 Time A. Nebulized versus Standard Local Application of Lidocaine during Flexible Bronchoscopy: A Randomized Controlled Trial ... Manuel Armin Reddemann, Annegret Müller, Christian Hübel, Tobias Müller. A recent study proposed a 32-base pair deletion in the CC-chemokine receptor 5 (CCR5) gene (CCR5-Δ32) interacting with the IL28B polymorphisms to influence spontaneous HCV clearance. The aim of this study was to anal... Background & aims: The natural course of HCV infection remains controversial. Pharmacological and nonpharmacological prevention of fentanyl-induced cough: a meta-analysis. Bring your services to over 450,000 developers. Due to our privacy policy, only current members can send messages to people on ResearchGate. Dreher M, Cornelissen CG, Reddemann MA, Müller A, Hübel C, Müller T. Nebulized versus standard local application of lidocaine during flexible bronchoscopy: a randomized controlled trial. Background: With the aging of the hepatitis C virus (HCV)-infected patient cohort and the availability of highly effective and tolerable treatment regimens, an increasing number of elderly patients are now eligible for HCV therapy. NTPDase2 has protective properties in liver fibrosis and may impact bile duct epithelial turnover. Das Murmeltier ist, ganz seinem Lebensraum angepasst, ein zäher Hund – bzw., zoologisch korrekter, ein zähes Erdhörnchen, wenn es zu kurz oder zu kalt gegart wird. View Tobias Müller’s profile on LinkedIn, the world’s largest professional community. Methods: The randomized trial took place in two urban hospitals in Germany. 2020 Jul;21(4):223-227. doi: 10.5152/TurkThoracJ.2019.19016. Tobias M. Müller's 96 research works with 1,930 citations and 8,459 reads, including: Negative Unjacketed Pore Modulus in Limestones? Only verified researchers can join ResearchGate and send messages to other members. Abstract. The introduction of direct-acting antivirals (DAA) has led to an increase in sustained virologic response rates (SVR), but is accompanied by higher treatment costs... Background: (DOC), Association of HLA-C inhibitory receptor genes KIR2DL2 and KIR2DL3 on viral clearance with and without therapy in combination with HLA-C genotypes. Thus, CXCL1 might contribute to HSC activation and fibrogenesis. He married Anna Miller on 16 June 1800. It is well established that polymorphisms in host genes, especially in components of the innate immune response, contribute to the phenom... Background & aims: Tobias Müller 1 , Christian Cornelissen 2 , Michael Dreher 2 Affiliations 1 Department of Pneumology and Intensive Care Medicine, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany. Infectious HCV particles bind to host lipoproteins such as low-density lipoproteins (LDL). This study investigated clinical and epidemiologic characteristics of elderly HCV-infected patients as well as the ef... Background & Aims We, therefore, investigated the use, effectiveness, and tolerability of DAAs in patients wi... Background He died on 4 May 1847, in his hometown, at the age of 71. Spart euch bei eurer Abishirtbestellung bis zum 31.01.2018 die Versandkosten! BLE, WiFi, Cellular, LoRaWAN and more. Nebulized lidocaine alone or combined with fentanyl as a premedication to general anesthesia in spontaneously breathing pediatric patients undergoing rigid bronchoscopy. , Summary: ProfDist is a user-friendly software package using the profile-neighbor-joining method (PNJ) in inferring phylogenies based on profile distances on DNA or RNA sequences. (DOC). Among patients newly infected with hepatitis C virus (HCV), only 20-30% clear the infection spontaneously. Facebook gives people the power to share and makes the world more open and connected. Einleitung In Deutschland sind mehr als 250 000 Patienten an einer chronischen Hepatitis C (CHC) erkrankt. Einleitung Der Hepatitis C Genotyp 1 ist der häufigste Genotyp in West- und Zentraleuropa. Ziele & Methoden: Wir bestimmten die PSC-IgG4 Pravalenz in zwei grosen unabhangi... To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C. Schmecken zu Hause fast immer besser als im Wirtshaus: Will man perfekte Kässpätzle haben, ist der richtige Käse entscheidend. Endobronchial administration of local anesthetics such as lidocaine is often used for cough suppression during bronchoscopy. 2018 Nov 21;19(1):227. doi: 10.1186/s12931-018-0926-5. They were the parents of at least 1 daughter. 2019 Jul;36(Supplement):S37-S89. Ich bin freier Journalist und als solcher bemüht, viel unterwegs zu sein, sei es in China, Mexiko, den USA oder Österreich. 2018 Nov 21;19(1):227. doi: 10.1186/s12931-018-0926-5. Madan K, Biswal SK, Tiwari P, Mittal S, Hadda V, Mohan A, Khilnani GC, Guleria R. Lung India. doi: 10.4103/lungindia.lungindia_108_19. Thus, CXCL1 might contribute to HSC activation and fibrogenesis. , 2019 Nov;11(11):4663-4670. doi: 10.21037/jtd.2019.10.59. Critical Examination of a Peculiar Laboratory Observation (DOC), (a) Association of combinations of IL28B SNP rs8099917 and HLA-C genotypes on viral clearance with and without therapy. Kim JE, Min SK, Chae YJ, Lee YJ, Moon BK, Kim JY. 2019 Jul-Aug;36(4):288-294. doi: 10.4103/lungindia.lungindia_348_18. In dieser Arbeit werden die Veränderungen der Baselinecharakteristika von 17 093 HCV-Patienten mit Genotyp 1a/1b, die im Zeitraum 2004–2018 in Deutschland antiviral therapiert wurden, analysiert. Aims: To investigate the prevalence of elevated IgG4 levels and to compare prognosis between patients with and without elevated IgG4 levels in serum in two European cohorts of pat... Unlabelled: We investigated if this polymorphism may... Unlabelled: Ziemlich gut, wenn Sie es denn kauen können. PEG‐interferon alpha‐2a (PEG‐IFNα‐2a) is the only effective treatment but its long‐term clinical impact is unclear. Recently, a tumor suppressive role for CHOP was demonstrated in lung cancer via regulation of tumor metabolism. Progress can only be measured in relation to the goal and the point d’appuis. To date, drug response genes have not proved as useful in clinical practice as was anticipated at the start of the genomic era. Erdem AO, Erel VK, Girit Ö, Erdoğan H, Özkısacık S, Yazıcı M. Turk Thorac J. Would you like email updates of new search results? We investigated whether Th2 cytokines disrupt the ba... Einleitung: PSC-Patienten mit erhohten IgG4 Serumspiegeln (PSC-IgG4+) zeigen nach neueren US- amerikanischen Studien einen aggressiveren Verlauf als Patienten mit „klassischer“ PSC ohne erhohte IgG4 Serumspiegel. Industry standard TLS stack and crypto library. Please enable it to take advantage of the complete set of features! Here, we investigated whe... Tumour surveillance via induction of TRAIL-mediated apoptosis is a key mechanism, how the immune system prevents malignancy. Here, we investigated whether the CXCL1 rs4074 polymorphism affects CXCL1 expression and progression of chronic hepatitis C virus (HCV) infection towards cirrhosis. As its pharmacokinetics depend on facilitated transmembrane transport, we assessed whether variants in genes that code for concentrative (... Einleitung: Genetische Variationen im Interleukin 28B (IL28B) Gen sind bei Hepatitis C Virus (HCV) Genotyp 1 infizierten Patienten mit dem Ansprechen auf eine PEG-Interferon-α/Ribavirin Therapie assoziiert. Become a partner. Ecosystem. The expression of (a) phospho-IRE1, total IRE1, phospho- eIF2α and total eIF2α an... JFH1 HCV fully infective cell system: (a) Titration of viral infection was done and TCID50 was calculated as described in the methods. DHCR7 Join ResearchGate to find the people and research you need to help your work. See the complete profile on LinkedIn and discover Laszlo’s connections and jobs at similar companies. The standard of hepatitis C antiviral therapy combines pegylated interferon-α with ribavirin. Stolz D, Chhajed PN, Leuppi J, Pflimlin E, Tamm M. Chest. ER stress occurs when protein folding capacity is exceeded. Use of lidocaine to prevent postoperative coughing after partial laryngectomy: comparison of three delivery methods. Es wurden insgesamt 5 Zeiträume betrachtet: (i)... Abstract Background Recent studies provide evidence that hepatocellular adenomas (HCAs) frequently take up gadoxetic acid (Gd-EOB) during the hepatobiliary phase (HBP). Unable to load your collection due to an error, Unable to load your delegates due to an error. Investigating the evolution of the DAA utilization patterns and treatment outcomes could... Background: Paediatr Anaesth. View Laszlo Tobias’ profile on LinkedIn, the world’s largest professional community. Nebulized dexmedetomidine-lidocaine inhalation as a premedication for flexible bronchoscopy: a randomized trial. While acute ER stress is lethal, chronic sub-lethal ER stress causes cells to adapt b... Responder operator curves for prediction of failure to clear virus on therapy based on clinical and genotyping data. Tobias Müller, Pia Andrée WertheimerAktualisiert vor 8 MinutenIdylle zwischen Felsflanken: Der Fählensee. Chronic hepatitis C virus infection is associated with a significant health burden. The study involved 237 patient... An isoleucine>methionine mutation at position 148 in the PNPLA3 gene (p.I148M, rs738409) has recently been identified as a susceptibility factor for liver damage in steatohepatitis. JOHN D. SKJERVEM CHIEF INVESTMENT OFFICER INVESTMENT DIVISION PHONE 503-431-7900 FAX 503-620-4732 STATE OF OREGON OFFICE OF THE STATE TREASURER 16290 SW UPPER BOONES FERRY ROAD TIGARD, OREGON 97224 OREGON INVESTMENT COUNCIL SEPTEMBER 20, 2017 MEETING MINUTES Members Present: Rukaiyah Adams, Tobias Read, … Dozens of leading companies trust Mbed OS. Here, we studied whether the PNPLA3 rs738409 polymorphism also affects predisposition to hepatocellular carcinoma (HCC). Conclusion: (TIF). It is therefore not surprising that in current Following infection, protein was extracted at the indicated time points. Hillsboro Arts & Crafts Fair, Hillsboro, Kansas. An exception is in the treatment of chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon-alpha and ribavirin (PegIFN/R). However, patients with impaired kidney function have been excluded from several clinical trials. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Tobias Müller is an e-mobility expert with a long background in the fields of automotive engineering and development processes. 2005 Sep;128(3):1756-60. doi: 10.1378/chest.128.3.1756. 2014 Apr;28(2):257-66. doi: 10.1007/s00540-013-1695-4. Financial Empowerment. Accessibility The aim of this study was to investigate the long‐term outcome after 48 weeks of pegylated interferon alfa‐2a therapy.We performed a retrospective f... Background&Aims Mohan A, Madan K, Hadda V, Tiwari P, Mittal S, Guleria R, Khilnani GC, Luhadia SK, Solanki RN, Gupta KB, Swarnakar R, Gaur SN, Singhal P, Ayub II, Bansal S, Bista PR, Biswal SK, Dhungana A, Doddamani S, Dubey D, Garg A, Hussain T, Iyer H, Kavitha V, Kalai U, Kumar R, Mehta S, Nongpiur VN, Loganathan N, Sryma PB, Pangeni RP, Shrestha P, Singh J, Suri T, Agarwal S, Agarwal R, Aggarwal AN, Agrawal G, Arora SS, Thangakunam B, Behera D; Jayachandra, Chaudhry D, Chawla R, Chawla R, Chhajed P, Christopher DJ, Daga MK, Das RK, D'Souza G, Dhar R, Dhooria S, Ghoshal AG, Goel M, Gopal B, Goyal R, Gupta N, Jain NK, Jain N, Jindal A, Jindal SK, Kant S, Katiyar S, Katiyar SK, Koul PA, Kumar J, Kumar R, Lall A, Mehta R, Nath A, Pattabhiraman VR, Patel D, Prasad R, Samaria JK, Sehgal IS, Shah S, Sindhwani G, Singh S, Singh V, Singla R, Suri JC, Talwar D, Jayalakshmi TK, Rajagopal TP. In patients with chronic hepatitis C virus (HCV) infection, several variants of the interleukin-28B (IL28B) gene have been shown to correlate significantly with a sustained virologic response (SVR). Privacy, Help Respir Res. Patients requiring bronchoscopy with endobronchial or transbronchial biopsy were randomly assigned to receive topical lidocaine either via syringe or via nebulizer. The purpose of our study was to investigate how to differentiate between Gd-EOB-enhancing HCAs and focal nodular hyperplasias (FNHs). View the profiles of people named Tobias Müller. Aim: 8600 Rockville Pike About Us. (DOC), Summary of associations between SNPs in Prevention and treatment information (HHS). Methods Consumption of sedative drugs and lidocaine was also compared between the two lidocaine administration approaches. Nebulized lidocaine for flexible bronchoscopy: a randomized, double-blind, placebo-controlled trial. Join ResearchGate to contact this researcher and connect with your scientific community. (DOC), Association of HLA-C activating receptor genes KIR2DS1 and KIR2DS2 on viral clearance with and without therapy. Recent evidence shows that determination of one single IL28B polymorphism, rs12979860, is sufficient for predicting treatment outcome. DHCR7 Our partners. Epidemiological data has only been provided from tertiary centres. National Library of Medicine This study investigated RASs before and after DAA failure in different genotype 4 subtypes and evaluated retreatment efficacies. In the present study, we investigated the influence of the CXCL1 rs4074 polymorphism on the occurrence of alcohol induced liver cirrhosis and hepatocellular carcinoma (HC... Genetic variations near the interferon lambda 3 gene (IFNL3, IL28B) are the most powerful predictors for sustained virologic response (SVR) in patients with chronic hepatitis C virus (HCV) infection, compared to other biochemical or histological baseline parameters. Sorry, you need to be a researcher to join ResearchGate. Seit 2014 sind zahlreiche potente direkt antivirale Substanzen gegen HCV zugelassen worden. TOBIAS MÜLLER Peuckert, Mehring open and accessible to wider, younger audiences as well as augmenting the concert experience as a whole. FOIA Samples of 195 genotype 4‐... PurposeTo differentiate subtypes of hepatocellular adenoma (HCA) based on enhancement characteristics in gadoxetic acid (Gd-EOB) magnetic resonance imaging (MRI).Materials and methodsForty-eight patients with 79 histopathologically proven HCAs who underwent Gd-EOB-enhanced MRI were enrolled (standard of reference: surgical resection). derstandard.at. , and Nebulized lignocaine for topical anaesthesia in no-sedation bronchoscopy (NEBULA): A randomized, double blind, placebo-controlled trial. Laszlo has 9 jobs listed on their profile. Action Items Presenter Tab 9:00-9:05 1. However, there are little data on the efficacy and safety of this approach, or on the consumption of sedative drugs and lidocaine during nebulized administration. Muscarinic acetylcholine receptor type 3 (mAChR3)-mediated signaling might be involved in the pathogenesis of chronic inflammatory biliary diseases such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). Affiliation 1 Division of Pneumology, University Hospital RWTH Aachen, Aachen, Germany. Methods: AASLD/IDSA treatment guidelines for hepatitis C virus (HCV) infection state that testing for quantitative HCV RNA can be considered at the end of antiviral treatment (EOT) with interferon‐free regimens. (DOC), Association of HLA-C inhibitory receptor genes KIR2DL2 and KIR2DL3 on viral clearance in combination with HLA-C genotypes based on two-digit genotyping. (DOC), Association of HLA-C activating receptor genes KIR2DS1 and KIR2DS2 on viral clearance with and without therapy in combination with HLA-C genotypes. J Anesth. Determination of the SAS- frequence in patients with bronchial carcinoma. (DOC), Comparison of HLA-C group 1 and 2 allele and genotype distribution from previous studies. Tight control of PRR signalling provides tolerance to physiological amounts of intestinal endotoxins in human bile to avoid constant innate immune activation in BECs. The apneaLink device is a standard screening tool for sleep apnea in clinical practice. eCollection 2019. All rights reserved. January 22, 2017. Long-term consequences are the development of liver cirrhosis and hepatocellular carcinoma. To explore the role of CHOP in hepatocarcinogenesis, we induced hepatocellular carcinoma (HCC) in wild type (wt) and CHOP knockout (KO) mice usin... CXCL1 (CXC chemokine-ligand-1) is a ligand for CXC chemokine receptor 2 expressed on hepatic stellate cells (HSC). Interleukin 28B (IL28B)... Genetic variation in the interleukin 28B (IL28B) gene has been associated with the response to interferon-alfa/ribavirin therapy in hepatitis C virus (HCV) genotype 1-infected patients. 2013 May;23(5):429-34. doi: 10.1111/pan.12081. However, it remains unclear how to respond to a detectable or even quantifiable HCV RNA result. Evaluation of Muscarinic Acetylcholine Receptor Type 3 Gene Polymorphisms in Patients with Primary Biliary Cholangitis and Primary Sclerosing Cholangitis, Real World Experience of Prescribing Tenofovir Alafenamide for Chronic Hepatitis B Patients in Germany, Assoziation des Polymorphismus rs7000921 im INTS10-Gen mit der Leberzirrhose bei kaukasischen Patienten mit chronischer Hepatitis B, Wirksamkeit und Sicherheit einer Sofosbuvir-Monotherapie bei Patienten mit chronischer Hepatitis E-Die HepNet SofE Studie, Persistenz von HCV Resistenz-assoziierten Substitutionen in NS3, NS5A und NS5B nach einem DAA Therapieversagen, Evolution of HCV patient characteristics and DAA regimens in the German Hepatitis C Registry (DHC-R) in 2014 and 2015, PS-179-Analysis of long-term persistence of HCV resistance-associated substitutions within NS, NS5A and NS5B in genotype 1 and 3 after DAA treatment failure, LBO-04-Efficacy and safety of sofosbuvir monotherapy in patients with chronic hepatitis E-The HepNet SofE pilot study, Hepatitis C therapy with direct antiviral agents in patients with advanced chronic kidney disease: real-world experience of the German Hepatitis C-Registry (Deutsches Hepatitis C-Register), Alcohol and Cannabis Consumption Does Not Diminish Cure Rates in a Real-World Cohort of Chronic Hepatitis C Virus Infected Patients on Opioid Substitution Therapy—Data From the German Hepatitis C-Registry (DHC-R), Deutsches Hepatitis C-Register (DHC-R) – eine Zwischenbilanz 4 Jahre nach Zulassung direkt antiviraler Substanzen (DAAs), Outcomes and costs of treating hepatitis C patients with second-generation direct-acting antivirals: results from the German Hepatitis C-Registry, Effectiveness and Safety of Direct-Acting Antiviral Combination Therapies for Treatment of Hepatitis C Virus in Elderly Patients: Results from the German Hepatitis C Registry, Die Auswirkung frühzeitiger Corticosteroidtherapie bei Patienten mit unklarer akuter Hepatitis, Clinical significance of detectable and quantifiable HCV RNA at the end of treatment with ledipasvir/sofosbuvir in GT1 patients, Impact of early corticosteroid treatment in patients with indeterminate acute severe hepatitis, Charakteristische ALT Verläufe nach Steroid Reduktion bei akuter Hepatitis ermöglichen eine Differenzierung von AIH und DILI, Serum IgG4 and long term outcome in patients with primary biliary cholangitis treated with ursodeoxycholic acid, Apolipoprotein E (APOE) allele frequencies in chronic and self-limited hepatitis C suggest a protective effect of APOE4 in the course of HCV infection, Einfluss des Apolipoprotein E Polymorphismus auf den Verlauf der Hepatitis C Virus (HCV) Infektion, Keratin-8-Mutationen prädisponieren nicht zur Entwicklung chronischer Lebererkrankungen insbesondere nicht zur kryptogenen Cirrhose, Predictive Value of Interferon-Lambda Gene Polymorphisms for Treatment Response in Chronic Hepatitis C, Validierung etablierter International Autoimmune Hepatitis Group (IAIHG) Diagnose-Scores in 246 Patienten mit gut charakterisierter autoimmuner Hepatitis in einer deutschen Universitätsklinik, The impact of elevated serum IgG4 levels in patients with primary sclerosing cholangitis, Polymorphisms in Melanoma Differentiation-Associated Gene 5 Link Protein Function to Clearance of Hepatitis C Virus, A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease, Evaluation of Liver Disease Progression in the German Hepatitis C Virus (1b)-Contaminated Anti-D Cohort at 35 Years After Infection, CCAAT/Enhancer-Binding Protein Homologous (CHOP) Protein Promotes Carcinogenesis in the DEN-Induced Hepatocellular Carcinoma Model, Influence of the CXCL1 rs4074 A Allele on Alcohol Induced Cirrhosis and HCC in Patients of European Descent, Association of IFNL3 rs12979860 and rs8099917 with Biochemical Predictors of Interferon Responsiveness in Chronic Hepatitis C Virus Infection, Assoziation zwischen IFNL3 Polymorphismen und klinischen Prädiktoren des Ansprechens auf eine interferon-basierte antivirale Therapie bei chronischer Hepatitis C, CCR5-Δ32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection, Increased T-Helper 2 Cytokines in Bile From Patients With IgG4-Related Cholangitis Disrupt the Tight Junction-Associated Biliary Epithelial Cell Barrier, Untersuchungen zur Bedeutung erhöhter IgG4 Serumspiegel in zwei großen unabhängigen europäischen Kohorten mit 345 Patienten mit primär sklerosierender Cholangitis (PSC), A Genetic Validation Study Reveals a Role of Vitamin D Metabolism in the Response to Interferon-Alfa-Based Therapy of Chronic Hepatitis C, Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection, Hepatocytes That Express Variants of Cyclophilin A Are Resistant to HCV Infection and Replication, 912 APOLIPOPROTEIN E4 ALLELE PROTECTS FROM CHRONIC HCV INFECTION, The toll-like receptor 2 (TLR2) -196 to -174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C, TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients, The CXCL1 rs4074 A allele is associated with enhanced CXCL1 responses to TLR2 ligands and predisposes to cirrhosis in HCV genotype 1-infected Caucasian patients, The PNPLA3 rs738409 148M/M Genotype Is a Risk Factor for Liver Cancer in Alcoholic Cirrhosis but Shows No or Weak Association in Hepatitis C Cirrhosis, Enhanced innate immune responsiveness and intolerance to intestinal endotoxins in human biliary epithelial cells contributes to chronic cholangitis, HCV Causes Chronic Endoplasmic Reticulum Stress Leading to Adaptation and Interference with the Unfolded Protein Response, IL28B, HLA-C, and KIR Variants Additively Predict Response to Therapy in Chronic Hepatitis C Virus Infection in a European Cohort: A Cross-Sectional Study, TH2 Zytokine wie IL-4 und IL-13 beeinträchtigen die Barrierefunktion und die Wundheilung humaner biliärer Epithelzellen (BECs), Kombination von IL28B Varianten (SNPs rs12979860 und rs8099917) verfeinert die Vorhersage für ein dauerhaftes Therapieansprechen bei chronischer Hepatitis C Virus (HCV)-Infektion, 232 TRAIL RECEPTOR I POLYMORPHISMS C626G AND A638C ARE ASSOCIATED WITH AN INCREASED RISK FOR THE DEVELOPMENT OF HEPATOCELLULAR CARCINOMA (HCC) IN HCV-INFECTED PATIENTS, 1304 TH2 CYTOKINE-MEDIATED BILIARY EPITHELIAL CELL (BEC) BARRIER DYSFUNCTION MAY CONTRIBUTE TO IMMUNOGLOBULIN G4 (IGG4) ASSOCIATED SCLEROSING CHOLANGITIS (IAC), 1157 NUCLEOSIDE TRANSPORTER SLC28A2/3 AND SLC29A1/2 GENETICS: PROTECTION AGAINST ANAEMIA IN CHRONIC HEPATITIS C PATIENTS RECEIVING RIBAVIRIN, 1358 DISTINCT, ALCOHOL-MODULATED EFFECTS OF PNPLA3 GENOTYPE ON PROGRESSION OF CHRONIC HEPATITIS C, Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients, A Duffy antigen receptor for chemokines (DARC) polymorphism that determines pro-fibrotic chemokine serum concentrations is not directly associated with severity of hepatitis C infection, Distinct, alcohol-modulated effects of PNPLA3 genotype on progression of chronic hepatitis C, Role of nucleoside transporters SLC28A2/3 and SLC29A1/2 genetics in ribavirin therapy, Prognose Untersuchungen zum Langzeitverlauf der primär sklerosierenden Cholangitis (PSC), Bedeutung von IL28B Gen Polymorphismen bei Hepatitis C Virus Genotyp 2 und 3 infizierten Patienten, Gestörte Endotoxin Toleranz in Gallengangsepithelien bei Patienten mit fortgeschrittener primär sklerosierender Cholangitis (PSC), Prävalenz erhöhter Immunglobulin G4 (IgG4) Konzentrationen bei Patienten mit chronisch-entzündlichen Lebererkrankungen unterschiedlicher Ätiologie, Innate barriers of respiratory virus infections, Department of General, Visceral and Transplantation Surgery. standard deviation: max drawdown: Are you Tobias Mueller? Essen, Trinken, Kochen, Schreiben. COVID-19 is an emerging, rapidly evolving situation. Käsknöpfle: Der Käse entscheidet. tobmueller@ukaachen.de. Associations between a functionally relevant polymorphism in the gene encoding the vitamin D 1α-hydroxylase (CYP27B1-1260 rs10877012) and the response to treatment with pegylated interferon-α (PEG-... Unlabelled: , and HCV-related hepatocellular carcinoma development, considering the SCCS as case-control study.

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